TECHNOLOGIE DE FABRICATION DES COMPRIMÉES D’ACIDE ASCORBIQUE. INFLUENCE DES MATERIAUX PRIMES
MATEESCU MONICA*1, TRANDAFIR ION 1, PETRESCU MANUELA 2 (1)UNIVERSITÉ DE CRAIOVA, FACULTÉ DE CHIMIE, DÉPARTEMENT DE CHIMIE PHISIQUE ET TECHNOLOGIE, RUE CALE BUCURESTI 170 B, CRAIOVA, *E-MAIL: MONIQUETTE2001@YAHOO.COM (2)S.C. PFIZER ROMANIA S.R.L., 179 SPLAIUL INDEPENDENTEI, SECT. 5, BUCURESTI,
We studied two different formulas for the tablets, with the addition substance (PVP) for the A formula in the solid state, and for the second formula, B in an aqueous solution. These both formulas were granulated and tableted in order to obtain the ascorbic acid tablets. These tablets were used for the study of the dissolving process of the active principle, and the influence of the PVP on the rate of this process.
