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DEVELOPMENT OF NEW ACCESS ROADS TO THE IMIDAZO[1,2-b]PYRIDAZINS DI- AND TRISUBSTITUTED DEVELOPPEMENT DE NOUVELLES VOIES D’ACCES AUX IMIDAZO[1,2-b]PYRIDAZINES DI- ET TRISUBSTITUEES

AHMED EL AKKAOUI 1 2, JAMAL KOUBACHI 1 2, SABINE BERTEINA-RABOIN 1 *, ABDERRAHIM MOUADDIB 2, GÉRALD GUILLAUMET 1
(1)INSTITUT DE CHIMIE ORGANIQUE ET ANALYTIQUE, UMR CNRS 6005, UNIVERSITÉ D’ORLÉANS, BP 6759, 45067 ORLÉANS CEDEX 2, FRANCE (2)FACULTÉ DES SCIENCES ET TECHNIQUES DE BÉNI-MELLAL, UNIVERSITÉ SOULTAN MOULAY SLIMAN BP 523, 23000 BÉNI-MELLAL, MAROC *CORRESPONDI

Issue:

SCSCC6, Volume IX, No. 2

Section:

Volume IX, No. 2 (2008)

Abstract:

In this paper we propose a new efficient and fast strategy for the synthesis of di- and tri-substituted derivates of imidazo[1,2 b]pyridazines via palladium-catalyzed couplings of Sonogashira, Heck and Stille type on the 6 chloro 3 iodo imidazo[1,2 b]pyridazines.

Keywords:

pallado-catalyzed coupling, imidazo[1, 2-b]pyridazines, synthesis.

Code [ID]:

CSCC6200809V02S01A0013 [0002079]

Full paper:

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