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CHARACTERIZATION OF A TEM CELL-BASED SETUP FOR THE EXPOSURE OF BIOLOGICAL CELL SUSPENSIONS TO HIGH-INTENSITY NANOSECOND PULSED ELECTRIC FIELDS (nsPEF)


SOUEID MALAK 1, KOHLER SOPHIE 1, O’CONNOR RODNEY P. 1, LEVEQUE PHILIPPE 1, ARNAUD-CORMOS DELIA 1
1. Institut de recherche XLIM, UMR CNRS 7252 Université de Limoges, 87060 Limoges, France

Issue:

PLUMEE, Number 1, Volume I

Section:

Issue No. 1 - Volume 3(2013)
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Abstract:

Cellular and intracellular structures of biological cells can be disturbed by exposure to nanosecond pulses electric field (nsPEF). The exposure system comprises two main parts: the pulses generator and the delivery device that containing biological medium. In this paper, we propose and characterize an open Transverse ElectroMagnetic (TEM) cell to expose a Petri dish filled with a biological suspension to nanosecond high voltage pulsed electric fields. Measurements of the reflection (S11) and transmission (S21) parameters show that empty TEM cell has a bandwidth of 2.9 GHz, whereas when the Petri dish is filled bandwidth is 1.7 GHz. TEM cell is well suited to deliver ultra-short pulsed electric fields with 1 ns duration.

Keywords:

Bioelectromagnetism, Transverse ElectroMagnetic (TEM) cell, S parameters, pulsed electric fields, high voltage.

Code [ID]:

PLUMEE201301V01S01A0058 [0004014]

Full paper:

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