Different studies proofed that nicotine is able to improve cognition performances, both to humans and animals [1]. In a previous study [6] we have demonstrated that S35836-1, a carbamate analogue of acetylcholine, is a specific ligand of nicotinic neural receptors of acetylcholine (nAChRs), with influence in Alzheimer and Parkinson diseases. The present paper presents new synthesis schemes of receptors with restricted conformational mobility.