The paper presents aspects on the cleaning of the soils contaminated with oil and salted water by using specialized microorganisms. For the artificial polluted land with oil and salted water has been determined the chemical and microbiological composition and it has been elaborated the pathway for a cleaning technology using microorganisms. Using this technology which involves the neutralization and regeneration of the polluted soils, the equilibrium between mineralization and humification has been reestablished by including the microbial proteins in the ecological cycle, with a very important role in the humification processes.