DEVELOPMENT OF NEW ACCESS ROUTES TO PYRAZOLO[1,5-a]PYRIMIDINE USING 4-HYDROXY-6-METHYLPYRAN-2-ONE DEVELOPPMENT DE NOUVELLES VOIES D’ACCES AUX PYRAZOLO[1,5-a]PYRIMIDINES A PARTIR DE LA 4-HYDROXY-6-METHYLPYRAN-2-ONE
IBTISSAM BASSOUDE1, 2, SABINE BERTEINA-RABOIN1*, EL MOKHTAR ESSASSI 2, GERALD GUILLAUMET 1 1. Institut de Chimie Organique et Analytique, Université d’Orléans, UMR CNRS 6005, 45067 Orléans Cedex2, France 2. Laboratoire de Chimie Organique Hétérocyclique, Faculté des Sciences, Avenue Ibn-Batouta INANOTECH, Rabat, Maroc *Corresponding author: sabine.berteina-raboin@univ-orleans.fr
In this work, we propose a new and fast strategy giving the pyrazolo[1,5-a]pyrimidines substituted at positions 5 and 7 via condensation of 3-amino-5-arylpyrazoles with 2-hydroxy-6-methylpyran-2-one in both conventional heating and microwave irradiation.
