The essential oil obtained by hydrodistillation of roots bark of Securidacaca longepedunculata Fers. (Polygalaceae) growing in Savalou, Biguinan and Gbegrou (Benin) were analyzed using capillary GC and GC/MS. Seven compounds representing (99.5%; 99.1%; 99.3%) respectively of the oils were identified. The major compound was found to be methyl salicylate respectively (98.0%; 98.6%; 98.7%). The antimicrobial activity of these oils was found to be high, and medium antiradical activity was observed.