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A NEW AND CONCISE SYNTHESIS OF 3-HYDROXYLATED 3-ARYLISOINDOLINONES
NOUVELLE TECHNIQUE D'ASSEMBLAGE DE 3-ARYLISOINDOLINONES HYDROXYLEES EN POSITION 3


MAGALI LORION 1, 2, AXEL COUTURE 1, 3, PIERRE GRANDCLAUDON 1, 2*
1. Université Lille Nord de France, F-59000 Lille, France
2. USTL, Laboratoire de Chimie Organique Physique, EA CMF 4478, BĂątiment C3(2), F-59655 Villeneuve d'Ascq, France
3. CNRS, UMR 8181 'UCCS', F-59655 Villeneuve d'Ascq, France
*Corresponding author: pierre.grandclaudon@univ-lille1.fr

Issue:

SCSCC6, Volume XV, No. 4

Section:

Volume XV, No. 4 (2014)

Abstract:

A new technique for the assembly of diversely substituted 3-hydroxy(alkoxy)-3-arylisoindolinones has been developed. This new synthetic route is based upon the anionic cyclization of suitably substituted halogenoaroyl acylamines as the key step and gives access to a variety of highly functionalized models.

Keywords:

diacylamines, metal-halogen conversion, anionic cyclization, Parham type cyclization, isoindolinones.

Code [ID]:

CSCC6201404V04S01A0001 [0004170]

DOI:

Full paper:

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