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CONTINUOUS CELL SORTING BY HIGH FREQUENCIES DIELECTROPHORESIS


THOMAS PROVENT1+, RĂ©MI MANCZAK1, SOFIANE SAADA2, CLAIRE DALMAY1, BARBARA BESSETTE2, PIERRE BLONDY1, GAĂ«LLE BEGAUD2, SERGE BATTU2, MARIE ODILE JAUBERTEAU2, FABRICE LALLOUĂ©2, ARNAUD POTHIER1
1 XLIM-UMR 7252, University of Limoges/CNRS, 87060 Limoges, France,
2 CAPTuR-EA 3842, University of Limoges, 87025 Limoges, France,
*thomas.provent@xlim.fr

Issue:

PLUMEE, Number 1, Volume IX

Section:

Issue No.1 - Volume 9 (2019)

Abstract:

This paper demonstrates the use of Ultra-High Frequency Dielectrophoresis to

sort populations of biological cells. The principal aim of this lab-on-chip cytometer is to

sort in a continuous flow different types of cells in suspension based on their dielectrics

properties. To achieve this objective, this cytometer combines hydrofluidics and repulsive

dielectrophoresis forces. We also show the importance to apply at cells a proper electric

field at a specific frequency range to produce different force intensities and associated

trajectory deflections. The device efficiency will be illustrated with an example of

mesenchymal cells sorting.

Keywords:

microfluidics, high frequency, dielectrophoresis, biologicals cells.

Code [ID]:

PLUMEE201901V09S01A0030 [0004998]

Note:

Full paper:

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