This paper demonstrates the use of Ultra-High Frequency Dielectrophoresis to
sort populations of biological cells. The principal aim of this lab-on-chip cytometer is to
sort in a continuous flow different types of cells in suspension based on their dielectrics
properties. To achieve this objective, this cytometer combines hydrofluidics and repulsive
dielectrophoresis forces. We also show the importance to apply at cells a proper electric
field at a specific frequency range to produce different force intensities and associated
trajectory deflections. The device efficiency will be illustrated with an example of
mesenchymal cells sorting. |