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LOW-FREQUENCY LOW INTENSITY MAGNETIC FIELD (50 Hz; 2.7 mT) INFLUENCES AND D2-DOPAMINE RECEPTOR BLOCKADE ON IMMUNE RESPONSE OF THE RAT


CÄ‚LIN MANIU, LUCIAN HRIŢCU, DANA HOROĹžANU, CRISTIAN SORIN CĂŽMPEANU

Issue:

SCSB, Volume X

Section:

Biochemistry

Abstract:

With the increased urbanization and the fact that electrical appliances are commonly used in our daily life, human beings and many other living organisms as well, are inevitably subject to the frequent exposure to low-frequency electromagnetic fields (EMFs) (Li and Chow, 2001). EMFs range from cosmic rays to the static magnetic fields of earth. Between these extremes is visible light, separating the whole range into ionizing and non-ionizing radiations (Jahn, 2000).

Magnetic field intensity is measured in international units called Tesla (T) or in the American units called Gauss (G). One unit Tesla equals 104 Gauss (Repacholi and Greenbaum, 1999).

Biological effects of low-frequency fields have been studied during the last three decades. Unfortunately, results of epidemiological studies in this research area have been contentious; results indicated that there is a link between the prevalence of adverse biologic effects and low-frequency field’s exposure, but there is not a significant association between insult and exposure (Anonymous, 1999; Orbach-Arbouys et al., 1999; Caplan et al., 2000). Both low- and high-intensity low frequency fields were subject to extensive investigations in an attempt to settle risk-assessment guidelines for the human exposure. Though residential exposure to low-frequency EMFs such as those from high-voltage powerlines results in low-intensity fields, possibility of human exposure to high-intensity fields has been increased lately due to the increased extent of modernisation.

Actually, some electric devices such as the magnetic resonance image (Schenck, 2000) could induce fields that may reach more than 1000-fold the intensity of the residential levels of EMFs. Further, human beings could be exposed to high intensity magnetic fields that may reach thousands Gauss from some magnetic belts and magnetic pads, as well as steel-belted radial tires (Milham et al., 1999).

Keywords:

LPS, sulpiride, low-frequency low intensity magnetic field, immune response.

Code [ID]:

SCSB200510V10S02A0006 [0002574]


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