Multiplication âin vitroâ is used routinely to generate a large number of high-quality clonal agricultural plants, including ornamental, medicinal and vegetable species. Micropropagation has significant advantages over traditional clonal propagation techniques. These include the potential of combining rapid large-scale propagation of new genotypes, the use of small amounts of original germplasm (particularly at the early breeding and/or transformation stage, when only a few plants are available), and the generation of pathogen-free propagules. This paper describes the first results of experiments carried out to induce organogenesis in tissue culture of Salvia officinalis L. under influence of different combinations of growth regulators. It also aims toward the identification of explant type, as well as the cultivation media and environmental factors that are optimal for the regeneration of plants with the same genetic inheritance.