This paper aims to implement and understand the mechanisms by which cervical lesions intervene in the pathogenesis of lesions precursor to neoplasia, as well as knowledge of their cytological investigation methods. The study is channeled towards a complete evaluation of the complex diagnosis of cervical intraepithelial lesions, based on classical methods of investigation that include the BabeĆ-Papanicolaou cytological examination. The cervix can be easily examined cytologically. The use of this method of investigation leads to the discovery of the disease in the early stages, 100% curable (Koss, 1989). The observations were made on cervico-vaginal smears. The vaginal secretion product was collected from 282 patients examined in the obstetrics-gynecology office "Clinic Center Hera" Bacau, for one year, March 2019 - March 2020. The samples were processed and clinically examined in the Medlife laboratory, Bacau . The working method used was Papanicolau in liquid medium, May-GrĂŒnwald-Giemsa staining, Papanicolau classification. Following the study, 73.85% of patients were identified with PN I and II smears, 8.83% were patients with PN III smears and 6.36% were patients with PN IV. Most cytological changes in the cervix occur in sexually active women over the age of 35.