Abstract
Aminocyanopyranes 1 react respectively with diethylmalonate, acetylacetone and ethylacetoacetate to give the corresponding functional pyranopyridines 2, 3 and 4. The reaction of the compounds 2, 3 and 4 with orthoesters then with primary amines affords respectively the pyranopyridinopyrimidines 5, 7 and 8. Refluxing of the functional pyranopyridines 2 with hydrazine in ethanol leads to the pyrimidinohydrazinopyridinopyranes 6. The structures of all prepared products were determined on the basis of their IR, 1H and 13C NMR spectra.
Cuvinte cheie
pyrane
pyranopyridine
pyrimidine
pyridinopyrimidine
pyranopyridinopyrimidine
aminopyridopyrane