Abstract
Derivatives of (1S, 2S)-2-amino-1-(4-nitrophenyl)- propane-1,3-diol were studied because of their potential biological activity. Using the electrogenerated intermediates (hydroxylamine and nitroso derivatives) N-sulphonylphenylhydroxylamines and benzoxazine diones were obtained with good yields. Their antibacterial activity was investigated on several gram-negative and gram-positive bacilli by two techniques: broth-dilution method and agar-dilution method.
Cuvinte cheie
electrosynthesis
hydroxylamines
nitrosoderivatives
redox cell