Abstract
In crystallization engineering, a crystallized powder of a pure component can be obtained in a selected solvent-antisolvent system. It has been proposed that binary water-alcohol mixed solvents can be used for this process. Isothermal titration calorimetry has been used to construct the solid-liquid equilibrium line in ternary systems containing the solute to precipitate and an aqueous-alcohol mixed solvent. Phase diagrams have been established over the whole concentration range for some benzene substituted derivatives, including o-anisaldehyde, 1,3,5-trimethoxybenzene and vanillin, in {water + alcohol} mixtures at different temperatures.
Cuvinte cheie
crystallization
solvent-antisolvent system
phase diagrams
water-alcohol solvents
benzene derivatives
isothermal calorimetric titration