INHERITED FACTORS INVOLVED IN DIABETES MELLITUS DETERMINISM

  • CRISTIAN TUDOSE
  • MIRELA M. CÎMPEANU
  • CRISTIAN S. CÎMPEANU
  • CĂLIN L. MANIU
  • LUCIAN HRIŢCU

Abstract

In the last years, huge progresses were made in the understanding of diabetes mellitus multifactorial determinism; candidate genes were proposed for both I and II types of diabetes and the polygenic transmission pathway of genetic predisposition was described (Hattersley and Pearson, 2006).
Still, diabetes remain a disease which surprises us by its high morbidity rates and its complications; despite the permanent progress of its treatment diabetes is a social disease, an important problem of public health and a permanent problem for the clinician and geneticist (Patraº et al., 2003).

Cuvinte cheie

Diabetes mellitus multifactorial inheritance recurrence risks