PROTEINOGRAM CHANGES IN MULTIPLE MYELOMA
DANIELA TIȚĂ(1), TATIANA CIUREA(2), IONUȚ STOICA(3*), DUMITRA RĂDUCANU(3*), DIANA IOANA TIȚĂ(4)
1. County Emergency Hospital, 2-4 Spiru Haret Street, Bacau, Romania 2. “Titu Maiorescu” University, Faculty of Medicine, Bucharest, Romania 3. “Vasile Alecsandri” University of Bacău, Faculty of Science, Department of Biology, Ecology and Environmental Protection, 157 Calea Mărăşeşti Street, 600115, Bacău, Romania 4. Colțea Clinical Hospital, Bucharest, Romania * Corresponding authors: Stoica I., Răducanu D. E-mail address: ionut_stoica23@yahoo.com, dora.raducanu@ub.ro
Abstract
Multiple myeloma is the third most common type of blood cancer, after leukemia and non-Hodgkin's lymphoma. It represents a complex medical challenge, and early diagnosis and appropriate treatment can improve the patient's prognosis and quality of life. The diagnosis of multiple myeloma is made with the help of serum protein electrophoresis, which shows the excess of a certain type of antibodies that is highlighted by a peak, called "monoclonal peak". The proteinogram changes in multiple myeloma are strongly expressed and characteristic, having diagnostic value, and, for greater certainty of the diagnosis, blood tests will be corroborated with bone radiography, computed tomography and marrow biopsy.