The mechanisms involved in the renal injury during liver disease are primarily by immune causes, by circulating immune complexes that are deposited at the level of the glomerular basal membrane, as well as by metabolic, toxic and infectious causes. Knowing and understanding the possible association of nephropathies with liver disease may be a possibility of preventing nephropathies with evolution towards acute or chronic renal failure. In the case of hepatitis C infection, renal impairment is one of the most important extrahepatic manifestations.