Alcohol addiction (alcoholism) is characterized by the regular consumption of large quantities of alcohol, by the inability of the individual to stay awake for a longer period of time. There are many causes e.g. genetic, psychological and social factors, that can lead to the installation of this condition, and as individuals continue to consume alcohol, changes occur that can compromise the structure and functions of the brain, determine the transition from controlled consumption, to abusive, chronic, difficult to control. Women and men metabolize alcohol differently, and alcohol consumption affects women more than men in the sense that they are more vulnerable to short and long - term effects and can develop diseases associated with alcohol consumption faster than men. Regardless of the severity of alcohol addiction, the effects it has on health, but also on the life of the individual, can be devastating. This study analyzes the variation of certain biochemical parameters: glucose, ALT (alanine aminotransferase), AST (aspartate aminotransferase), GGT (gamma glutamyltransferase), which are useful in the early detection of cellular damage caused by excessive ethanol consumption in different patient groups. The results obtained reflected differences between sexes, ages, and the risk factors monitored.