DEVELOPMENT OF NEW ACCESS ROADS TO THE IMIDAZO[1,2-b]PYRIDAZINS DI- AND TRISUBSTITUTED DEVELOPPEMENT DE NOUVELLES VOIES D’ACCES AUX IMIDAZO[1,2-b]PYRIDAZINES DI- ET TRISUBSTITUEES
In this paper we propose a new efficient and fast strategy for the synthesis of di- and tri-substituted derivates of imidazo[1,2 b]pyridazines via palladium-catalyzed couplings of Sonogashira, Heck and Stille type on the 6 chloro 3 iodo imidazo[1,2 b]pyridazines.