Nanosecond Pulsed Electric Fields (nsPEFs) are pulsed electric fields with high-intensities (few MV / m) and ultra-short durations (a few nanoseconds). These electromagnetic fields are used for biomedical applications such as cancer treatment. The application of the nsPEFs can be carried out by different exposure devices. In this article, four wire electrode devices are characterized in the frequency domain to assess their adaptation to nsPEFs exposures. The results show that these devices are capable of applying nsPEFs of 10 ns durations