A NEW RESEARCH ON BIOLOGICAL ACTIVITY OF (2S,3S)-1,4-BIS-SULFANYLBUTANE-2,3-DIOL
CORINA TOADER 1, IRINA ZARAFU 2*, ION BACIU 2 (1)NATIONAL INSTITUTE OF PNEUMOLOGY âMARIUS NASTAâ, 90, VIILOR ST., BUCHAREST, ROMANIA (2)UNIVERSITY OF BUCHAREST, FACULTY OF CHEMISTRY, 90-92, PANDURI ST., BUCHAREST, ROMANIA *CORRESPONDING AUTHOR: ZARAFUIRINA@YAHOO.FR
One of the key points in tuberculosis control programs is the early confirmation of the diagnostic through Koch bacilli detection. Therefore, this study is trying to highlight the role of digestion-decontamination agents in microscopic detection of M-Tuberculosis, in order to determine the ability of a smear made from respiratory sample to identify which specimens would be culture positive for M. tuberculosis. The research methodology has been based on comparison of three types of smears processed by standard technique and by NALC treatment respiratory specimens, respectively by a new tested mucolitic reagent, dithiothreitol. During each stage of preparation process, AFB microscopic sensitivity has been assessed by Ziehl-Neelsen and auramine-rhodamine staining methods.
