SYNTHESIS, REACTIVITY AND BIOLOGICAL ACTIVITY OF QUINOXALIN-2-ONE DERIVATIV

E.M. ESSASSI
LABORATORY OF HETEROCYCLIC ORGANIC CHEMISTRY, “MOHAMMED V” UNIVERSITY, AGDAL-RABAT, MOROCCO
H. BENZEID
LABORATORY OF HETEROCYCLIC ORGANIC CHEMISTRY, “MOHAMMED V” UNIVERSITY, AGDAL-RABAT, MOROCCO
R. BOUHFID
INSTITUTE OF NANOMATERIALS AND NANOTECHNOLOGY, INANOTECH, RABAT, MOROCCO
S. FERFRA
LABORATORY OF HETEROCYCLIC ORGANIC CHEMISTRY, “MOHAMMED V” UNIVERSITY, AGDAL-RABAT, MOROCCO
Y. KANDRI RODI
LABORATORY OF APPLIED ORGANIC CHEMISTRY
Y. RAMLI
LABORATORY OF HETEROCYCLIC ORGANIC CHEMISTRY, “MOHAMMED V” UNIVERSITY, AGDAL-RABAT, MOROCCO

Abstract

Quinoxalines have a great interest in various fields and particularly in chemistry, biology and pharmacology. It enabled the researchers to develop many methods for their preparations and to seek new fields of application. In this review, we’ll expose different methods of synthesis of the quinoxalin-2-one, its reactivity and finally we’ll discuss the various biological activities of its derivatives.

Cuvinte cheie

quinoxalin-2-one synthesis reactivity alkylation cycloaddition biological properties