DEVELOPMENT OF NEW ACCESS ROUTES TO PYRAZOLO[1,5-a]PYRIMIDINE USING <br>4-HYDROXY-6-METHYLPYRAN-2-ONE <br>DEVELOPPMENT DE NOUVELLES VOIES D’ACCES AUX PYRAZOLO[1,5-a]PYRIMIDINES A PARTIR DE LA 4-HYDROXY-6-METHYLPYRAN-2-ONE
IBTISSAM BASSOUDE1, (2), SABINE BERTEINA-RABOIN1(*), EL MOKHTAR ESSASSI(2), GERALD GUILLAUMET(1)
1. Institut de Chimie Organique et Analytique, Université d’Orléans, UMR CNRS 6005, 45067 Orléans Cedex2, France
2. Laboratoire de Chimie Organique Hétérocyclique, Faculté des Sciences, Avenue Ibn-Batouta INANOTECH, Rabat, Maroc
*Corresponding author: sabine.berteina-raboin@univ-orleans.fr
Abstract
In this work, we propose a new and fast strategy giving the pyrazolo[1,5-a]pyrimidines substituted at positions 5 and 7 via condensation of 3-amino-5-arylpyrazoles with 2-hydroxy-6-methylpyran-2-one in both conventional heating and microwave irradiation.