EXTRACTION, ANALYSIS AND BIOLOGICAL ACTIVITIES OF A FAMILY OF DITERPENES <br/> EXTRACTION, ANALYSE ET EVALUATION DES ACTIVITES BIOLOGIQUES D’UNE FAMILLE DE DITERPENES<br/>

  • EMMANUELLE VILLEDIEU
    Institut de Chimie Organique et Analytique, UMR 6005, Université d’Orléans, BP 6759 Orléans cedex 2, France
  • EMILIE DESTANDAU
    Institut de Chimie Organique et Analytique, UMR 6005, Université d’Orléans, BP 6759 Orléans cedex 2, France
  • CHANTAL PICHON
    Centre de Biophysique Moléculaire UPR 4301 CNRS, Rue Charles Sadron, 45071 Orléans cedex 2, France
  • SABINE BERTEINA-RABOIN
    Institut de Chimie Organique et Analytique, UMR 6005, Université d’Orléans, BP 6759 Orléans cedex 2, France
    sabine.berteina-raboin@univ-orleans

Abstract

Our study deals with a diterpenoid lactone family isolated from Andrographis paniculata. Our work was to perform extraction method, HPLC analysis and purification starting from commercial products. It led to the isolation of several pure compounds. Then, we investigated the effect of these molecules and the crude extracts towards immunostimulation.

Cuvinte cheie

andrographolide anti-inflammatory diterpenes HPLC plant extract