EXTRACTION, ANALYSIS AND BIOLOGICAL ACTIVITIES OF A FAMILY OF DITERPENES <br/> EXTRACTION, ANALYSE ET EVALUATION DES ACTIVITES BIOLOGIQUES D’UNE FAMILLE DE DITERPENES<br/>
EMMANUELLE VILLEDIEU(1), EMILIE DESTANDAU(1), CHANTAL PICHON(2), SABINE BERTEINA-RABOIN(1)
1. Institut de Chimie Organique et Analytique, UMR 6005,
Université d’Orléans, BP 6759 Orléans cedex 2, France
2. Centre de Biophysique Moléculaire UPR 4301 CNRS,
Rue Charles Sadron, 45071 Orléans cedex 2, France
*Corresponding author: sabine.berteina-raboin@univ-orleans
Abstract
Our study deals with a diterpenoid lactone family isolated from Andrographis paniculata. Our work was to perform extraction method, HPLC analysis and purification starting from commercial products. It led to the isolation of several pure compounds. Then, we investigated the effect of these molecules and the crude extracts towards immunostimulation.