Were investigated 30 men with a diagnosis of hypertension. In these subjects we studied the biochemical response of the heart, pursuing diagnostic value of biochemical indicators: triglycerides, cholesterol, HDL, LDL, creatinine, troponin T, lactad dehydrogenase, aminotransferases (SGOT, SGPT), and creatine which causes changes the circulatory system and blood pressure increase. Investigated subjects were grouped by sex and three age categories: 36-50 years, 51-65 years and above 65 years. Age group most affected, in our case the range was 36-50 years, where significant changes occur specific indicators for cardiovascular disease: LDL-cholesterol, triglycerides, troponin T, LDH and SGOT.