Abstract
A new technique for the assembly of diversely substituted 3-hydroxy(alkoxy)-3-arylisoindolinones has been developed. This new synthetic route is based upon the anionic cyclization of suitably substituted halogenoaroyl acylamines as the key step and gives access to a variety of highly functionalized models.
Cuvinte cheie
diacylamines
metal-halogen conversion
anionic cyclization
Parham type cyclization
isoindolinones