They were investigated 30 men and 30 women with a diagnosis of hypertension. These subjects were studied biochemical response of the heart, aiming biochemical indicators of diagnostic value: triglycerides, cholesterol, HDL, LDL, creatinine, troponin T, lactad dehydrogenase, aminotransferase (SGOT, SGPT) and creatine that cause changes to the circulatory system and increased blood pressure. Investigated subjects were grouped by gender and three age categories: 36-50 years, 51-65 years and over 65 years. In both women and men, pathological changes, raising, there is only three biochemical parameters of the study - triglycerides, LDL-cholesterol, and LDH. In men appear in addition, total cholesterol and elevated aminotransferase, SGOT and SGPT). The age group most affected is women over 50 years and between 51-65 and over 65, confirming other studies that claim incidence and severity of hypertension is lower in women before menopause. The age group most affected was the men between 36-50 years, where significant changes occur specific indicators for cardiovascular disease: LDL-cholesterol, triglycerides, troponin T, LDH and TGO.