COVID-19 may present as a silent asymptomatic infection, a mild upper respiratory tract disease or a severe illness characterized by fulminant inflammation, systemic coagulopathy and severe damage to the lungs and cardiovascular system and other organs. Acute respiratory distress syndrome (ARDS) and multiple organ dysfunctions are among the leading causes of death and severe forms in patients diagnosed with CoV-19. Severely ill patients (CoV-19) have hyper inflammation and associated biomarkers provide useful information for risk assessment. Moreover, the serum levels of inflammatory markers such as: Il-6, ferritin, CRP, D-dimers are closely related to the severity of the disease.