STUDY ON THE VARIATION OF FERRITIN CONCENTRATION IN PATIENTS TESTED FOR HEALTH ASSESMENT
TATIANA CIUREA(1), DANIELA TIŢĂ(2*), RAMONA BELOIU(3), MARIA PRISECARU(4), IONUT STOICA(4)
1. Bagdasar-Arseni Emergency Clinical Hospital, Bucharest, e-mail: ciurea_t@yahoo.com; 2. Bacau Emergency County Hospital, Romania; e-mail: danielatita2007@yahoo.com; 3. LifeDiagnostic Bucharest 4. „Vasile Alecsandri” University of Bacau, Faculty of Science, Department of Biology, Bacau, Romania, e-mail: prisecaru_maria@yahoo.com; ionut_stoica23@yahoo.com * Corresponding author’s
Abstract
The serum level of ferritin, the protein synthesized in the spleen, bone marrow, liver, correlates with the body’s iron deposits and total iron binding capacity (TIBC). Moreover, the blood concentration of ferritin is more sensitive and specific than sideremia and TIBC. Ferritin is an acute phase reagent, being increased in patients with acute or chronic liver disease, kidney disease, alcoholism, neoplasm, hyperthyroidism, infections and inflammation. The determination and correlation of the values obtained for ferritin with HLG, ESR, sideremia and other acute phase reactants (fibrinogen, C-Reactive Protein), allow the correct establishment of the diagnosis and an adequate treatment.