Abstract
This study has the aim of verifying the
histological alterations in the hepatic tissue of Rana
ridibunda when exposed to 0.4mg/g body weight of
Actara 25WG at 4-6ºC, respectively at 22-24ºC. The
toxic was administrated with intraperitoneal shots
(one shot every two days, in a scheme of three
weeks).
A technique of light microscopy was used. At
the end of the experiment. we have observed the
presence of biliary pigment in the citosol. Some
hepatocytes lost cellular contour.
Karyomegalia and polyploidy together with
accumulation of infiltrates were also observed. A
large zone of fibrosis was present between
hepatocytes and around blood vessels. The
histological changes were more powerful at 22-24ºC.
Cuvinte cheie
frog
thiamethoxame
liver
karyomegalia
accumulation of infiltrates
fibrosis